The incident occurred on Wednesday night at a gas station in the Johannesburg suburb of Florida.
The 24-year-old Kaizer Chiefs star was waiting to be seen when he was approached by unidentified gunmen who told him to exit the vehicle.
One of the suspects is said to have departed the area in Fleurs’ automobile following the incident.
“The suspects pointed [at] him with a firearm and took him out of his vehicle, then shot him once on the upper body,” Gauteng police spokesperson Lieutenant Colonel Mavela Masondo told local media.
The club stated that police were managing the situation and that further information would be released in due time.
Sports Minister Zizi Kodwa said he was “saddened that yet another life has been cut short due to violent crime”.
Defender Fleurs joined Kaizer Chiefs last year after previously playing for SuperSport United.
The former Under-23 international will represent South Africa at the Tokyo Olympics in 2021.
He has not yet played for the senior national team, although he was expected to make his debut soon.
According to their website, Kaizer Chiefs characterize Fleurs as a “classy defender” with “great technical abilities”.
He started his career in 2013 at the Ubuntu Cape Town Academy, according to local media.
The Premier Soccer League has announced that a moment of silence will be observed at all top-flight and second-tier games this weekend in memory of Fleurs.
“We woke up to the heart-breaking and devastating news of the passing of this young life,” South African Football Association president Danny Jordaan said in a statement.
