KwaZulu-Natal Premier Sihle Zikalala has opened a brand new quarantine site inside the Clairwood hospital in Durban.
The extension and renovations are estimated at over R200-million.
The facility took six months from start to completion.
Zikalala says the province is prepared to fast track the development of similar healthcare facilities at other sites.
KwaZulu-Natal currently stands at 106 565 confirmed COVID-19 cases, with 82 599 recoveries and 1789 deaths.
Over 11-million screenings have taken place and over 223 000 tests have been conducted.